Chemical Patents

NK Patent Law has an experienced chemical patents practice. Our chemical patents group works with Fortune 100 companies, startup companies, contract research organizations (CROs), and public and private universities.

The chemical patents group is international in scope, seeking patent protection on behalf of clients in many foreign jurisdictions. Additionally, the chemical patent practice provides freedom-to-operate analysis and clearance services for entry of new chemical products and processes into the United States and foreign countries, as well in due diligence matters for intellectual property acquisition and monetization.

Our chemical practice also includes advising clients on complex corporate, joint venture, and licensing matters as they arise, and the firm represents both investors and startup companies.

Dr. Laura Kiefer leads the chemical patents practice. She holds a PhD from Duke University in Biochemistry and can be contacted here. Dr. Kiefer previously worked in-house and managed the entire patent portfolio for Affinergy, LLC, a leader in peptide and enzyme research and creation.

Ashley Johnson worked in biochemical research in both the pharmaceutical industry and at the University of North Carolina at Chapel Hill. Previously, Mrs. Johnson worked 8 years as in-house Patent and Trademark Counsel at a major packaging corporation in South Carolina, with a focus on Medical Devices and related product innovations.


 

Representative Work

U.S. Patent No. 8,859,223
“Compositions and methods for imaging beta-secretase activity in living cells and organisms”
Molecular probes are provided for use in fluorescence microscopy procedures for monitoring beta-secretase enzyme (BACE) activity in living cells and organisms. The probes may be useful for monitoring Alzheimer’s Disease-associated BACE in living cells. By fluorescing when hydrolyzed by BACE, the probes can allow for real-time spatial and temporal assessment of enzymatic activity without the need for mutated cell lines or antibodies. The molecular probes may also be used to screen libraries of potential BACE inhibitors or evaluate how external stimuli affect BACE activity.
U.S. Patent No. 8,067,021
“Methods and compositions for delivery of growth factor to fibrous connective tissue”
The presently disclosed subject matter relates to a peptide composition for non-covalently localizing fibrous connective tissue-inducing growth factor to a surface of an implant, the composition comprising a peptide having binding affinity for a surface material of an implant coupled to a peptide having binding affinity for a fibrous connective tissue-inducing growth factor. Methods are provided for delivering fibrous connective tissue-inducing growth factor GDF-7 in an amount effective to promote fibrous connective tissue repair and fibrous connective tissue formation. Also provided are methods of applying the peptide composition to an implant by contacting the composition with a surface of the implant; and kits comprising the compositions.
U.S. Patent No. 7,968,677
“IFBM’s to promote the specific attachment of target analytes to the surface of orthopedic implants”
Molecular probes are provided for use in fluorescence microscopy procedures for monitoring beta-secretase enzyme (BACE) activity in living cells and organisms. The probes may be useful for monitoring Alzheimer’s Disease-associated BACE in living cells. By fluorescing when hydrolyzed by BACE, the probes can allow for real-time spatial and temporal assessment of enzymatic activity without the need for mutated cell lines or antibodies. The molecular probes may also be used to screen libraries of potential BACE inhibitors or evaluate how external stimuli affect BACE activity.